through and through

• 彻头彻尾的机会主义

  out and out opportunism

• 彻头彻尾的捏造

  complete and utter fabrication

• 这是彻头彻尾的谎言。

  This is a lie through and through.

• 这些都是彻头彻尾的诽谤。

  That is slander through and through.