苦于无能为力

worry about not being able to do anything

苦于没有时间

worry about not having time

我苦于不识字。

My illiteracy is causing me problems.

他急着想动身，苦于没有车子。

He's in a hurry to get going, but not having a car is causing him problems.

他的生活苦于其他人。

His life is tougher than other peoples'.