老祖母对孙子可疼得厉害。

The grandmother loves the child dearly.

牙疼

toothache

头疼

headache

头疼得厉害

have a bad headache

疼得厉害

hurt terribly

疼得要命

hurt like hell

孩子把头撞疼了。

The kid's head hurt because he bumped it.

我把手碰得很疼。

I knocked my hand and it really hurts.

气候一变我的关节就疼。

My joints ache whenever the temperature changes.