没有门路或办法to have no way of doing something
办这样的事,我可没门儿。
I've got no way of handling matters like this.
表示不可能expresses impossibility
凭你这成绩想考大学,没门儿。
There's no way you could apply for university with results like yours.
表示不同意expresses disagreement
你想一个人独占,没门儿!
So you want to be top dog? We'll see about that!
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