失去和谐to become disharmonious

• 倘有一环失谐，则如江河淤塞，堤坝崩溃，弄得不可收拾。

  If there is any dissonance, it will be like silt blocking the rivers and the dams will collapse; the situation will become out of control.

• 有时你在盛怒之下，动作就会失谐。

  Sometimes when you are in a rage, your movements become clumsy.